RAD140, also known as Testolone, is a new investigational drug that is popular for its muscle-building effects.
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RAD-140, also known as Testolone, is a new investigational drug that is popular for its muscle-building effects. RAD-140 belongs to a class of compounds called selective androgen receptor modulators, or SARMs.
SARMs work by binding to androgen receptors that are found in different areas of the body. Normally these receptors interact with androgens, which are a group of steroid hormones. Androgens like testosterone, dihydrotestosterone, and androstendione are naturally produced by the body.
SARMs and testosterone have similar effects because they work on the same receptor. Some of these effects include influencing the muscles, bones, and the liver.
The advantage of SARMs is that they are selective about where they work. They mostly target muscle and bone tissues while having minimal effects on other organs. This allows SARMs to potentially treat hormone-related or muscle-wasting disorders with fewer side effects.
RAD-140 has become popular in men with low testosterone levels who want to avoid testosterone replacement therapy but are looking to maintain their physical and sexual performance.
RAD-140 works by selectively stimulating androgen receptors in the body. It targets receptors in the muscle and bone and has little to no effect on the reproductive organs.
The structure of RAD-140 is also very different from the structure of steroid hormones like testosterone. This means the body isn’t able to convert RAD-140 into other hormones like estrogen that may have undesirable effects.
This compound also stimulates muscle growth by promoting the development of muscle cells and proteins.
Based on a study, RAD-140 activates receptors in regions of the brain that are injured. This triggers a signal called the MAPK pathway that helps protect cells.
Increasing muscle mass
Enhance speed, stamina and endurance during high-intensity workouts
Greater anabolic effect than testosterone
May reduce the side effects of testosterone
Bodybuilding resources usually recommend a dose of 10 to 30 mg per day.
For women, a dose of 5 to 10 mg per day is recommended.
Users typically cycle RAD-140 for 8 to 12 weeks. The off-cycle can vary, some recommend they last as long as the cycles, while others think that a shorter off-cycle of 6-8 weeks is sufficient. Veterans will tailor these depending on their labs, checking to see how the cycles affected their liver markers and hormone balance.